Conditions

Understanding Phantom Limb Pain

Phantom Limb Pain (PLP) is a form of neuropathic pain that occurs after amputation of a limb or part of a limb, when a person continues to feel pain that seems to come from the missing body part. It is a well-recognised condition, caused by changes in the nervous system and brain that occur after amputation — the brain continues to receive and interpret signals as if the limb were still present.

Phantom limb pain can appear soon after surgery or develop months later, and its intensity and frequency vary greatly between individuals. It is distinct from stump pain, which originates in the remaining part of the limb, though the two can overlap.

Typical symptoms include:

  • Burning, stabbing, cramping, or shooting pain in the absent limb
  • Tingling, itching, or “pins and needles” sensations
  • Pain triggered by touch, cold, or emotional stress
  • A feeling that the missing limb is in an awkward or twisted position
  • Pain that fluctuates over time, often worse at night or during fatigue

Phantom limb pain reflects the brain’s attempt to adapt to the loss of sensory input from the missing limb. Specialist care focuses on calming the nervous system and retraining the brain’s pain response.

Wessex Pain Clinic

How We Diagnose

At Wessex Pain Clinic, diagnosis begins with a comprehensive assessment. We explore your surgical history, the timing and pattern of symptoms, and whether pain arises mainly from the phantom limb, the stump, or both.

We also assess for:

  • Nerve injury or neuroma formation (painful nerve-end growths in the stump)
  • Scar sensitivity or muscle spasm
  • Referred pain from the spine or remaining limb

Investigations may include:

  • Ultrasound to identify neuromas or local nerve entrapment
  • MRI for deeper tissue assessment when required
  • Diagnostic nerve blocks to confirm the pain’s source

Understanding whether the pain is local (from the stump) or central (from the nervous system) allows us to tailor a precise treatment plan.

Wessex Pain Clinic 159 of 242 Edit
Lifestyle and Complementary Therapies

Our physiotherapists and rehabilitation partners play a crucial role in recovery. They use:

  • Mirror therapy and graded motor imagery to retrain the brain’s perception of the missing limb
  • Desensitisation and stretching exercises to improve comfort at the stump
  • Posture and prosthesis training to optimise balance and function

Our pain psychology team provides support for managing anxiety, trauma, and adjustment after amputation, using Cognitive Behavioural Therapy (CBT), Acceptance and Commitment Therapy (ACT), and mindfulness to improve coping and resilience.

Hydrotherapy and gentle movement exercises can further help reduce muscle tension and improve circulation.

This multidisciplinary model ensures that every aspect of phantom limb pain — physical, neurological, and emotional — is addressed in a coordinated way. At Wessex Pain Clinic, we work as a team and meet regularly to discuss complex, treatment resistant or unusual cases. As such you will often receive the expertise of several pain consultants. We believe that we are one of very few pain clinics to offer this.

Medications

We may prescribe:

  • Neuropathic pain medicines such as amitriptyline, duloxetine, gabapentin, or pregabalin to calm overactive nerve pathways
  • Anti-inflammatory drugs (NSAIDs) to reduce local stump irritation
  • Topical treatments (lidocaine or capsaicin) for stump hypersensitivity
  • NMDA receptor modulators (in specialist use) to reduce abnormal nerve signalling
Interventional Procedures

Our consultants are experts in image-guided pain management techniques that target nerve pain precisely, including:

  • Peripheral nerve blocks or neuroma injections at the amputation site
  • Pulsed Radiofrequency (PRF) treatment to modulate overactive nerves without damaging them
  • Lidocaine infusions to calm central nerve hypersensitivity
  • Spinal Cord Stimulation (SCS) — an advanced therapy for severe or persistent phantom limb pain, which works by altering pain signal transmission in the spinal cord
Our treatment for phantom limb pain is multidisciplinary, consultant-led, and highly individualised, addressing the neurological, physical, and emotional aspects of pain.

Treatment at Wessex Pain Clinic

Treatments