Genicular Nerve Radiofrequency Ablation (Rhizolysis)

Wessex Pain Clinic

Genicular Nerve Radiofrequency Ablation (Rhizolysis)

Genicular nerve radiofrequency ablation (RFA) is a minimally invasive procedure designed to reduce persistent knee pain by targeting the small sensory nerves that carry pain signals from the knee joint. It is typically offered when knee pain continues despite physiotherapy, medication, or surgery, and can provide longer-lasting relief than diagnostic nerve blocks or joint injections. The procedure is performed by a consultant in pain medicine under precise image guidance.

How the Procedure Works

Pain from knee arthritis or previous injury can persist because the nerves supplying the knee continue to send pain signals even when the main cause of inflammation has been treated. The genicular nerves are small branches around the knee that transmit these signals to the brain.

In radiofrequency ablation, your consultant uses ultrasound guidance to place very fine needles near these nerves. A brief test stimulation confirms the correct position before controlled radiofrequency energy is applied. This heat treatment interrupts the nerves’ ability to transmit pain signals while leaving nearby movement and strength nerves unaffected.

Because nerves can slowly regenerate over time, the benefit may lessen with time, however many get long term relief. The procedure can be repeated if necessary.

Wessex Pain Clinic

What Conditions It Can Help With

Genicular nerve RFA may be recommended for:
Persistent knee pain due to osteoarthritis
Ongoing pain after knee replacement or other surgery (in selected cases)
Pain not adequately controlled with medication, physiotherapy, or joint injections
Patients who are not suitable for further surgical intervention

Aimed Benefits

The aim of the procedure is to reduce chronic knee pain and stiffness, allowing better mobility and comfort in daily life. It can help you engage more effectively with physiotherapy and exercise programmes, and may reduce the need for regular pain medication. While not a cure for arthritis, many patients experience significant and sustained pain relief.

What to Expect

We usually would only carry this procedure out after a successful, but short lived, genicular nerve block

Genicular nerve RFA is usually carried out as a day-case procedure under local anaesthetic. Image guidance (X-ray or ultrasound) is used throughout to ensure accurate placement of the needles. Sedation is usually offered.
After the treatment, you will rest for a short time before going home the same day. Some mild discomfort or bruising around the knee is common for a few days. Improvement in pain typically develops gradually over the following weeks.

Driving advice: You should not drive that day if receiving any sedation. Our procedures do vary on whether it is possible to drive home yourself. Please seek advice from your consultant about driving advice. If you are seeing us for an injection and planning to drive, please check with us beforehand about whether it will be possible to drive yourself home afterwards.

Risks and Considerations

All procedures carry some risks, which will be discussed in detail with you during your consultation. These may include temporary discomfort, bruising, or numbness around the treatment area. You will have the opportunity to ask questions, and formal consent will always be obtained before any procedure is carried out.

Combined Approach / Multidisciplinary Care

At Wessex Pain Clinic we find that the best results come from combining medical treatments with active rehabilitation. Procedures are often most effective when paired with physiotherapy, movement-based exercise, and — where appropriate — psychological support. This comprehensive approach addresses both the physical and emotional aspects of pain and supports longer-term improvement.

Key Points Summary

  • Consultant-led, image-guided procedure
  • Uses radiofrequency energy to interrupt pain signals from the knee
  • Aims to provide longer-lasting pain relief than injections
  • Suitable for chronic knee pain due to arthritis or post-surgical pain
  • Sedation available for theatre-based procedures
  • May reduce need for medication and improve mobility

Disclaimer

Results vary between individuals and cannot be guaranteed. Your consultant will discuss whether this procedure is appropriate for you.

At Wessex Pain Clinic, we work as a team and meet regularly to discuss complex, treatment resistant or unusual cases. As such you will often receive the expertise of several pain consultants. We believe that we are one of very few pain clinics to offer this. Wessex Pain Clinic provides consultant-led assessment and treatment for acute and chronic pain conditions. Our multidisciplinary team includes Consultant Pain Specialists, Physiotherapists and Psychologists, offering evidence-based interventions alongside rehabilitation and self-management support. We welcome patients from across Hampshire, Dorset, Wiltshire, Surrey and Sussex, including Winchester, Basingstoke, Southampton, Portsmouth, and Chichester – with both in-clinic appointments and remote consultations available across the wider Wessex region.